Abstract: The present study aims to investigate the Cramer-Rao Bound (CRB) for estimating the direction and velocity of the moving target using the moving bistatic MIMO radar system in the clutter environment. Firstly, the bistatic MIMO radar signal model with the moving transmit and receive arrays is constructed. And the general CRB expression is derived for the direction and velocity of the moving multi-target contaminated by the clutter echoes. Then this study gets the closed-form CRB expressions for the Direction Of Departure (DOD), Direction Of Arrival (DOA) and velocity of a moving target in the clutter-free environment. The impact of some parameters on the CRB is analyzed depending on the closed-form expression. Theoretical analyses and computer simulations show that the estimation performance of the direction and velocity in a clutter-free environment is better than those of the clutter environment. The velocities of the arrays and target have no impact on the estimation performance of the target DOD (DOA), but strongly affect the estimation accuracy of the target velocity. The estimation performance of target velocity can lead to degradation as the velocity of arrays and target increase.