Abstract: The spectrum of the clutter is spatially-temporally coupled in the airborne MIMO radar. Based on the knowledge that the location of the ground clutter in angle-Doppler domain is mainly dependent on the velocity of the airplane and the radar parameters, a novel two dimensional pulse-to-pulse canceller is designed to suppress the clutter signals more efficiently. As a pre-filtering tool before the conventional Moving Target Indication (MTI) and the sub-optimal dimension-reduced Spatial-Temporal Adaptive Processing (STAP) algorithms, the method can enhance the performance of moving target detection. The experimental results demonstrate that the proposed pre-filtering approach can effectively suppress the clutter and can be flexibly constructed according to different array configurations. Moreover, the proposed method can gain a better performance for detecting the high speed moving target.