Abstract: The parameter estimation performance for the moving bistatic MIMO radar is studied. First, the bistatic MIMO radar signal model with both the transmit and receive arrays being moving is given and the general Cramer- Rao Bound (CRB) expression for the parameters of multi-target is derived. Then, the closed-form CRBs for Direction Of Departure (DOD) and Direction Of Arrival (DOA) of single target are obtained. The impact of some parameters on the CRB is analyzed when both the transmit and receive array are moving. Theoretical analyses and computer simulations show that: the DOD/DOA estimation performance will be improved as the velocity of the moving transmitter/receiver increases, while the other angle (DOA/DOD) estimation performance will degrade. When the aspect angle of moving transmitter/receiver is vertical to the DOD/DOA and the other site is parallel to the DOA/DOD, the best DOD/DOA estimation performance is obtained.