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Volume 42 Issue 10
Oct.  2020
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Yanfeng WANG, Zhenzhen ZHANG, Panru WANG, Junwei SUN. Molecular Circuit Design of Two-bit Gray Code Subtracter Based on DNA Strand Displacement[J]. Journal of Electronics & Information Technology, 2020, 42(10): 2557-2565. doi: 10.11999/JEIT190880
Citation: Yanfeng WANG, Zhenzhen ZHANG, Panru WANG, Junwei SUN. Molecular Circuit Design of Two-bit Gray Code Subtracter Based on DNA Strand Displacement[J]. Journal of Electronics & Information Technology, 2020, 42(10): 2557-2565. doi: 10.11999/JEIT190880

Molecular Circuit Design of Two-bit Gray Code Subtracter Based on DNA Strand Displacement

doi: 10.11999/JEIT190880
Funds:  The National Key R and D Program of China for International S and T Cooperation Projects (2017YFE0103900), The Joint Funds of the National Natural Science Foundation of China (U1804262), The State Key Program of National Natural Science of China (61632002), The Central Plains Thousand Talents Program (204200510003), The Open Fund of State Key Laboratory of Esophageal Cancer Prevention and Treatment (K2020-0010, K2020-0011)
  • Received Date: 2019-11-04
  • Rev Recd Date: 2020-06-07
  • Available Online: 2020-07-11
  • Publish Date: 2020-10-13
  • DNA strand displacement technology has the characteristics of spontaneity, parallelism, programmability and dynamic cascade, which is widely used to solve mathematical problems. In this paper, a two-bit subtracter is designed by using Gray code encoding and DNA strand displacement technology to extend the operation of DNA subtraction. Finally, Visual DSD software is used to simulate the two-bit subtracter. The circuit, with the strong parallelism and expansibility, achieves the expected function. It can be used in combination with other biochemical circuits.
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