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Volume 42 Issue 6
Jun.  2020
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Article Navigation >  Journal of Electronics & Information Technology  > 2020  >  42(6): 1374-1382
Yafei DONG, Wenxiao HU, Mengyao QIAN, Yue WANG. DNA Aptamer-based Fluorescence Biosensor[J]. Journal of Electronics & Information Technology, 2020, 42(6): 1374-1382. doi: 10.11999/JEIT190860
Citation: Yafei DONG, Wenxiao HU, Mengyao QIAN, Yue WANG. DNA Aptamer-based Fluorescence Biosensor[J]. Journal of Electronics & Information Technology, 2020, 42(6): 1374-1382. doi: 10.11999/JEIT190860
shu

DNA Aptamer-based Fluorescence Biosensor

doi: 10.11999/JEIT190860
  • 1.

    College of Life Science, Shaanxi Nomal University, Xi’an 710119, China

  • 2.

    School of Computer Science, Shaanxi Normal University, Xi’an 710119, China

Funds:  The National Natural Science Foundation of China (61572302), The Natural Science Basic Research Plan in Shaanxi Province of China (2020JM-298)
  • Received Date: 2019-11-01
  • Rev Recd Date: 2020-03-14
    • Available Online: 2020-04-03
  • Publish Date: 2020-06-22
    Abstract
  • In recent years, with the rapid development of DNA nanotechnology, fluorescence biosensors based on DNA as aptamer are studied and constructed by a large number of scholars in order to realize the sensitive and rapid detection of target materials. As a new branch of DNA nanotechnology, fluorescence biosensors based on DNA aptamer have great application. The fluorescence biosensors based on DNA aptamers are summarized. The realization of fluorescence signal contains fluorescent dyes and non-fluorescent dye labeled. Enhancement of fluorescence signals involve enzyme-assisted, chain replacement reaction and both of all mediated target circulation and signals amplification strategy. On this basis, the fluorescence biosensor based on DNA aptamer is prospected and some suggestions are put forward.
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